(Contributed by dalin, February 17, 2008, in the forums see the original post )
Bioneers is a forum for connecting the environment, health, social justice, and spirit within a broad progressive framework. Their activities include running a large annual conference, live webcasts of this conference and other smaller conferences, a radio series, a newsletter and youth program.
CiviCRM is used to manage their 70k contacts, accept donations, manage 2100 memberships, and integrate with their custom conference registration application (CiviEvent wasn't even a twinkling in anyone's eye when this application was developed, but may be used in the future).